International AIDS Society, IAS, 2010. 6 p.
International AIDS Society, IAS
Substantial progress has been made in expanding access to antiretroviral therapy (ART) for adults and children living with HIV and preventing vertical transmission. However, the scale-up of ART programmes has also drawn attention to a number of knowledge gaps related to clinical management and ART programme delivery for women and children. Issues such as the development of weight-adjusted dosage recommendations and paediatric formulations, the impact of antiretroviral prophylaxis to prevent vertical transmission on future treatment options for women, and optimal ART delivery models to maximize access and minimize loss to follow-up are some of the questions which continue to challenge health care providers, programme managers and the populations they serve. Through a 10-month consultative process involving investigators, clinicians, civil society and UN agencies, the International AIDS Society (IAS) and its international partners have identified 20 priority research questions to address these critical knowledge gaps. While the focus of this agenda is treatment research, it is also critical to recognize the importance of linking treatment and prevention research for women and children, a topic explored in other documents and by other groups.
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