This Teacher Guide contains the information, assessment tasks and sample lesson plans for teaching about HIV/AIDS and STIs in TVET institutions, in Papua New Guinea. The course will: build upon the Personal Development subject in Grade 6-8; be honest, accurate and "tok stret" about HIV/AIDS, STIs and reproductive health; be practical, student centred and participatory; be sensitive to the feelings, backgrounds and culture of students; follow the principles of the Department of Education (DoE) HIV/AIDS Policy (2005); promote a life skills approach based on universal human values of care, love and respect.; be written by Papua New Guinean teachers for Papua New Guinean teachers.