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This report looks at data from a multistage probability sample of 1,093 Croatian youth aged 18-24 years in 2005. Regression was used to investigate relationships between HIV-related knowledge, attitudes and sexual behavior and condom use at first and last sexual encounter and consistent use of condoms. Results found that positive attitudes towards condoms and condom use at first intercourse were predictors for condom use at most recent intercourse and overall consistent use of condoms (OR: 1.3). Sex education programs should be given to youth before they become sexually active.