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This report on the baseline data from three countries (Mexico, Thailand and South Africa) provides information on the HIV-prevention needs of school-based youth. It focuses on select key variables including HIV knowledge, attidudes toward people living with HIV/AIDS, confidence in acquiring and using condoms, and reported sexual behaviour. This information and other data obtained from the studies has helped shape the school-based interventions by informing teachers about student needs. It can also be helpful to others planning HIV prevention programmes for youth in similar settings.