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President's Emergency Plan for AIDS Relief (PEPFAR's) response to the millions of children impacted by HIV/AIDS was to designate 10% of its budget to securing their futures, making it the leading supporter of programs reaching orphan and vulnerable children (OVC) programs globally. This article describes the evolution of PEPFAR's OVC response based on programmatic lessons learned and an evergrowing understanding of the impacts of HIV/AIDS. …
South Africa is disproportionately affected by the HIV/AIDS epidemic. The country has less than one percent of the world's 15-24-year-olds, yet these young people account for approximately 14 percent of all global HIV infections among this age group. Young women are at particular risk among 15-24 year-olds, four times as many females as males are living with HIV (16.9 percent versus 4.4 percent) and girls are becoming infected at much faster rates than boys. …
