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Situated on major drug trafficking routes that bring heroin, cocaine, and methamphetamine from Mexico into the United States, Tijuana and Juarez experience high rates of local drug use and rank first and second, respectively, in prevalence of illicit drug use within the country. Sex tourism is another feature shared by Tijuana and Juarez. Both cities have 'tolerance zones' where sex work is openly practiced and, in the case of Tijuana, even regulated by the authorities
Pasa la Voz (spread the word) is a methodology used to prevent HIV using respondent-driven sampling to reach hard to access women. An organization in Ciudad Juarez (Programa Companeros) initiated a one-to-one approach to reaching at-risk and hard to reach women in the area using promotoras (outreach workers) from September 2005 to January 2006. The implementation of Pasa la Voz came on its heels and had success in increasing the number of women agreeing to get tested for HIV (11.9% to 49.9%) and decreasing testing time from 22.70 hours to 3.68 hours per test.