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This population size estimation (PSE) was undertaken in order to inform HIV prevention programming for key populations in the fight against HIV in Sierra Leone. This PSE focused on female sex workers (FSWs), men who have sex with men (MSM) and people who inject drugs (PWID) because these groups are typically the first and hardest affected by HIV, and addressing their needs to prevent HIV can prevent or diminish the effect of HIV/AIDS on the general population. …